Keratinocyte proximity and contact can play a significant role in determining mesenchymal stem cell fate in human tissue...
Published in The FASEB Journal
Bone marrow-derived human mesenchymal stem cells (hMSCs) possess multipotent differentiation capabilities and are a potent source of paracrine factors. We show how the epidermal keratinocyte can direct hMSC differentiation selectively. Keratinocytes and hMSCs were either cocultured in physical contact (contact cocultures), or separated without phys...
