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News 49 Publications 2 Members

Eicosanoids and Keratinocytes in Wound Healing.

Raja Sivamani

Published in Advances in Wound Care

Significance: Eicosanoids are biologically active lipid mediators derived from arachidonic acid that are important in injury and inflammatory responses. Cyclooxygenase-1 and cyclooxygenase-2 mediate the production of prostanoids, whereas 5-lipoxygenase mediates the production of leukotrienes and hydroxyeicosatetraenoic acids. These lipid mediators ...

Microneedles and transdermal applications.

Raja Sivamani Liepmann, D Maibach, Hi

Published in Expert Opinion on Drug Delivery

With the limitations of oral drug delivery and the pain and needle phobias associated with traditional injections, drug delivery research has focused on the transdermal delivery route. A formidable barrier to transdermal drug delivery is the stratum corneum, the superficial layer of the skin. In the last 10 years, microneedles were proposed as a me...

A Systematic Review of Lactoferrin Use in Dermatology.

Hassoun, La Raja Sivamani

Published in Critical Reviews in Food Science and Nutrition

The use of hormonal agents in the treatment of acne.

Hassoun, La Chahal, Ds Raja Sivamani Larsen, Ln

Published in Seminars in Cutaneous Medicine and Surgery

Hormones and androgens play an important role in the pathogenesis of acne. Multiple hormonal modulators are now available for the treatment of acne. The efficacies and side effects of currently available hormonal agents are reviewed here including the use of oral contraceptives, spironolactone, flutamide, cyproterone acetate, finasteride, and corte...

Shedding light on sunscreens and their labels: Testing policies need to match actual use.

Raja Sivamani Ghiya, M Maibach, Hi

Published in American Journal of Preventive Medicine

Alopecia as the Presenting Symptom of Syphilis.

Ornelas, J Agbai, On Kiuru, M Raja Sivamani

Published in Dermatology online journal

Alopecia can be one of the many symptoms of secondary syphilis and the clinical presentations include essential syphilitic alopecia or symptomatic syphilitic alopecia. In this report, we present a case of a patient with essential syphilitic alopecia whose sole presenting symptom of syphilis was alopecia. Despite an initial negative rapid plasma rea...

A novel keratin 5 mutation in a familial cluster.

Lev-Tov, H Raja Sivamani Burrall, B

Published in Dermatology online journal

We report a case of epidermolysis bullosa simplex (EBS) associated with a family cluster of EBS and a novel KRT5 mutation. The case is presented in the context of recent advances in the study of the disease.

Acupuncture as a Treatment Modality in Dermatology: A Systematic Review.

Ma, C Raja Sivamani

Published in The Journal of Alternative and Complementary Medicine

Novel use of terpenoids for treatment of dermatologic diseases: a systematic review of clinical trials.

Tuong, W Walker, L Raja Sivamani

Published in The Journal of Alternative and Complementary Medicine

Advice for medical students interested in dermatology: perspectives from fourth year students who matched.

Alikhan, A Raja Sivamani Mutizwa, Mm Aldabagh, B

Published in Dermatology online journal

We present perspectives from four fourth year medical students who matched into dermatology that highlight the factors they believed helped them most. The purpose is to offer advice to medical students interested in dermatology. We divide the paper into four areas of discussion: academics, extracurricular activities, research, and mentorship. All f...

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