Fruits are rich in antioxidants and ripe for topical therapy.
Published in Journal of Dermatological Treatment
UVB-sensitive solar urticaria possibly associated with terbinafine.
Published in Dermatology online journal
Solar urticaria is an uncommon condition characterized by erythema and whealing shortly after exposure to ultraviolet (UV) and/or visible light. We report a 25-year-old woman with an erythematous, edematous, pruritic reaction minutes after sun exposure while she was taking terbinafine for onychomycosis. Phototesting revealed a UVB-sensitive urticar...
Effective Strategies for the Management of Pyoderma Gangrenosum.
Published in Advances in Wound Care
Squamous cell carcinoma in the setting of chronic hidradenitis suppurativa; report of a patient and update of the litera...
Published in Dermatology online journal
Squamous cell carcinoma (SCC) developing in chronic hidradenitis suppurativa (HS) is rare, but failing to recognize the condition may have significant consequences. Dermatologists must be aware of the potential for malignant transformation and should have a low threshold for biopsy when clinical presentation is atypical. Herein we describe a 64-yea...
A Report of Two Patients with Darier Disease and Hidradenitis Suppurativa.
Published in Pediatric Dermatology
We report two unique cases of patients with Darier disease and hidradenitis suppurativa. Although it is unknown whether there is a connection between the two diseases, it is possible that an interaction between sarcoendoplasmic reticulum calcium transport ATPase and Notch homolog 1, translocation-associated (Drosophila) caused both diseases in thes...
The economic burden of sunscreen usage.
Published in Dermatology online journal
Excessive sun exposure is known to be the leading cause of skin cancer. The direct cellular damage inflicted by the ultraviolet (UV) radiation from the sun results in premature aging, DNA damage, and mutations that ultimately lead to skin cancer. Sunscreens are highly recommended to protect against UV radiation. However, little research has been co...
Cedarwood Oil as Complementary Treatment in Refractory Acne.
Published in The Journal of Alternative and Complementary Medicine
Acne vulgaris is a widely prevalent chronic skin disease. Although multiple treatments are available, acne can sometimes be refractory to these treatments. The use of alternative medical therapies has increased within dermatology and for acne. This case report describes a patient in whom the addition of cedarwood oil was helpful in controlling acne...
Plant-based modulation of Toll-like receptors: an emerging therapeutic model.
Published in Phytotherapy Research
Plant-based extracts present a large source of natural immune modulators, many of which have been used in traditional medicine for centuries. Recent research efforts have identified plant extracts as potential modulators of Toll-like receptors (TLRs), the first responders in immunological defenses in normal and disease conditions. This review aims ...
Chondroid syringoma: case report and review of the literature.
Published in Dermatology online journal
An 84-year-old man presented with an enlarging bluish, painless subcutaneous nodule on the glabella. The lesion had been excised 4 years prior and was diagnosed as chondroid syringoma, but had gradually regrown. The recurrent lesion was treated by surgical re-excision. Histopathological examination was again consistent with chondroid syringoma, and...
Acute wounding alters the beta2-adrenergic signaling and catecholamine synthetic pathways in keratinocytes.
...Published in Journal of Investigative Dermatology
Keratinocyte migration is critical for wound re-epithelialization. Previous studies showed that epinephrine activates the beta2-adrenergic receptor (B2AR), impairing keratinocyte migration. Here, we investigated the keratinocyte catecholamine synthetic pathway in response to acute trauma. Cultured keratinocytes were scratch wounded and expression l...
